Article
Evaluating the role of non-alcoholic fatty liver disease in cardiovascular diseases and type 2 diabetes: a Mendelian randomization study in Europeans and East Asians.
International journal of epidemiology - 6 Jun 2023
Au Yeung Shiu Lun, Borges Maria Carolina, Wong Tommy Hon Ting, Lawlor Deborah A, Schooling C Mary
Abstract excerpt
BACKGROUND: Whether non-alcoholic fatty liver disease (NAFLD) causes cardiovascular disease (CVD) and type 2 diabetes (T2D) is unclear and possible differences between ethnicities have not been thoroughly explored. We used Mendelian randomization (MR) to assess the role of NAFLD in CVD and T2D risk in Europeans and East Asians. METHODS: We conducted a MR study using genetic predictors of alanine aminotransferase...
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