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Article

RB1‑promoter methylation in glioblastoma: A rare event in glioblastoma

2 Jun 2023

Abstract excerpt

The retinoblastoma gene (RB1) is a tumor suppressor gene that serves a key role in the development of numerous tumor diseases that can be downregulated by DNA methylation within its promoter region. The present study analyzed the methylation status of the RB1 promoter of 85 glioblastomas to assess its role in this tumor. To elucidate the underlying mechanism, RB1 promoter methylation was evaluated using...

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PMID: 37264960
DOI: 10.3892/or.2023.8580

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