Dopaminergic neuronal imaging in genetic Parkinson's disease: insights into pathogenesis.

doi:10.1371/journal.pone.0069190

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Article

Dopaminergic neuronal imaging in genetic Parkinson's disease: insights into pathogenesis.

PloS one - 1 Jan 2013

McNeill Alisdair, Wu Ruey-Meei, Tzen Kai-Yuan, Aguiar Patricia C, Arbelo Jose M, Barone Paolo, Bhatia Kailash, Barsottini Orlando, Bonifati Vincenzo, Bostantjopoulou Sevasti, Bressan Rodrigo, Cossu Giovanni, Cortelli Pietro, Felicio Andre, Ferraz Henrique B, Herrera Joanna, Houlden Henry, Hoexter Marcelo, Isla Concepcion, Lees Andrew, Lorenzo-Betancor Oswaldo, Mencacci Niccolo E, Pastor Pau, Pappata Sabina, Pellecchia Maria Teresa, Silveria-Moriyama Laura, Varrone Andrea, Foltynie Tom, Schapira Anthony H V

Abstract excerpt

OBJECTIVES: To compare the dopaminergic neuronal imaging features of different subtypes of genetic Parkinson's Disease. METHODS: A retrospective study of genetic Parkinson's diseases cases in which DaTSCAN (123I-FP-CIT) had been performed. Specific non-displaceable binding was calculated for bilateral caudate and putamen for each case. The right:left asymmetry index and striatal asymmetry index was calculated....

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PMID: 23935950
DOI: 10.1371/journal.pone.0069190
PMCID: PMC3720622

Genes

PINK1
CIT

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