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ARMADiLLO: a web server for analyzing antibody mutation probabilities.

Nucleic acids research - 5 Jul 2023

Martin Beem Joshua S, Venkatayogi Sravani, Haynes Barton F, Wiehe Kevin

Abstract excerpt

Antibodies are generated by B cells that evolve receptor specificity to pathogens through rounds of mutation and selection in a process called affinity maturation. Somatic hypermutation is mediated by an enzyme with DNA sequence context-dependent targeting and substitution resulting in variable probabilities of amino acid substitutions during affinity maturation. We have previously developed a program called...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37260077
DOI: 10.1093/nar/gkad398
PMCID: PMC10320107

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