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AbDiver: a tool to explore the natural antibody landscape to aid therapeutic design

10 Mar 2022

Abstract excerpt

MOTIVATION: Rational design of therapeutic antibodies can be improved by harnessing the natural sequence diversity of these molecules. Our understanding of the diversity of antibodies has recently been greatly facilitated through the deposition of hundreds of millions of human antibody sequences in next-generation sequencing (NGS) repositories. Contrasting a query therapeutic antibody sequence to naturally...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35274671
DOI: 10.1093/bioinformatics/btac151

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