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Article

FOXL2 Mutation Analysis of Ovarian Sex Cord-Stromal Tumors: Genotype-Phenotype Correlation With Diagnostic Considerations.

International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Jul 2018

Buza Natalia, Wong Serena, Hui Pei

Abstract excerpt

Correlation of FOXL2 mutation status with morphologic features and reticulin staining patterns was performed in a comprehensive single-institutional cohort of ovarian sex cord-stromal tumors. Fifty-one cases were included, 35 of which were morphologically diagnosed as adult granulosa cell tumor, 4 as Sertoli-Leydig cell tumor, 11 as fibroma/fibrothecoma and 1 as a thecoma. Of the adult granulosa cell tumors, 31...

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Identifiers

PMID: 28700438
DOI: 10.1097/PGP.0000000000000426

Genes

FOXL2

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FOXL2 Mutation Analysis of Ovarian Sex Cord-Stromal Tumors: Genotype-Phenotype Correlation With Diagnostic Considerations.PMID 28700438Read ↗

Novel FOXL2 Mutation in an Ovarian Adult Granulosa Cell Tumor: Report of a Case With Diagnostic and Clinicopathologic Implications.Semantic proximity Read ↗

FOXL2 Mutation Status in Sex Cord-stromal Tumors Cannot be Predicted by Morphology.Semantic proximity Read ↗

FOXL2 mutation is absent in uterine tumors resembling ovarian sex cord tumors.Semantic proximity Read ↗

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Ovarian cellular fibromas lack FOXL2 mutations: a useful diagnostic adjunct in the distinction from diffuse adult granulosa cell tumor.Semantic proximity Read ↗

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