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Article

Evaluation of molecular analysis in challenging ovarian sex cord-stromal tumours: a review of 50 cases.

Pathology - 1 Oct 2020

Stewart Colin J R, Amanuel Benhur, De Kock Leanne, Apellaniz-Ruiz Maria, Carrello Amerigo, Giardina Tino, Grieu-Iacopetta Fabienne, Thomas Marc A, Foulkes William D

Abstract excerpt

Molecular profiling was performed in 50 problematic ovarian sex cord-stromal tumours (SCSTs) most of which were seen in consultation. Following analysis, 17 were classified as adult granulosa cell tumour (AGCT), 16 of which showed a FOXL2 sequence variant (mutation); the initial favoured diagnosis in five of the cases was benign thecoma/fibrothecoma. Thirteen tumours ultimately classified as cellular fibroma or...

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PMID: 32782216
DOI: 10.1016/j.pathol.2020.06.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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