Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interplay between Müller cells and microglia aggravates retinal inflammatory response in experimental glaucoma

1 Dec 2021

Abstract excerpt

BACKGROUND: Glaucoma, the leading cause of irreversible blindness, is a retinal neurodegenerative disease, which results from progressive apoptotic death of retinal ganglion cells (RGCs). Although the mechanisms underlying RGC apoptosis in glaucoma are extremely complicated, an abnormal cross-talk between retinal glial cells and RGCs is generally thought to be involved. However, how interaction of Müller cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glaucoma and retinal disorders
Share to Adenosine and Purinergic Signaling
Share to Retinal Diseases and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34952606
DOI: 10.1186/s12974-021-02366-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interplay between Müller cells and microglia aggravates retinal inflammatory response in experimental glaucomaPMID 34952606Read ↗

The role of Müller glia and microglia in glaucomaSemantic proximity Read ↗

Molecular signaling from microglia impacts macroglia autophagy and neurons survival in glaucomaSemantic proximity Read ↗

A possible mechanism of microglia-photoreceptor crosstalk.Semantic proximity Read ↗

Evaluation of Neuroprotective And Immunomodulatory Properties of Mesenchymal Stem Cells in An Ex-vivo Retinal Explant ModelSemantic proximity Read ↗

AIBP protects retinal ganglion cells against neuroinflammation and mitochondrial dysfunction in glaucomatous neurodegenerationSemantic proximity Read ↗

Cytokines IL-1β and IL-10 are required for Müller glia proliferation following light damage in the adult zebrafish retinaSemantic proximity Read ↗

A journey into the retina: Müller glia commanding survival and deathSemantic proximity Read ↗

Caspase-8-mediated inflammation but not apoptosis drives death of retinal ganglion cells and loss of visual function in glaucomaaSemantic proximity Read ↗

CHOP Deletion and Anti-Neuroinflammation Treatment With Hesperidin Synergistically Attenuate NMDA Retinal Injury in MiceSemantic proximity Read ↗

Microglia Regulate Neuroglia Remodeling in Various Ocular and Retinal InjuriesSemantic proximity Read ↗

Changes in Retinal Glial Cells with Age and during Development of Age-Related Macular DegenerationSemantic proximity Read ↗

Systemic inflammation induced by lipopolysaccharide aggravates inherited retinal dystrophySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.