Article
Pathologic, immunologic, and clinical analysis of the microsatellite instability phenotype in endometrial carcinoma.
Human pathology - 1 Sept 2023
Mackinnon Alexander Craig, Johnson Colin M, Robin Adam, Christiansen Lyle, Hanbazazh Mehenaz, Summey Rebekah M, Chandrashaker Darshan, Harada Shuko, Bradley Williams H
Abstract excerpt
The objective of this study was to determine if quantifying the microsatellite instability (MSI) phenotype could serve as a biomarker for clinical and immunologic features of deficient mismatch repair (dMMR) endometrial cancer (EC). Patients with EC undergoing hysterectomy whose tumors demonstrated dMMR were included. Immunohistochemistry (IHC) of mismatch repair proteins and polymerase chain reaction analysis of...
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