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Noninvasive detection of microsatellite instability in patients with endometrial cancer

18 Jan 2023

Abstract excerpt

The analysis of mismatch repair proteins in solid tissue is the standard of care (SoC) for the microsatellite instability (MSI) characterization in endometrial cancer (EC). Uterine aspirates (UAs) or circulating-DNA (cfDNA) samples capture the intratumor heterogeneity and provide a more comprehensive and dynamic molecular diagnosis. Thus, MSI analysis by droplet-digital PCR (ddPCR) in UAs and cfDNA can provide a...

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PMID: 36650670
DOI: 10.1002/ijc.34435

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