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Article

Diagnostic Performance of Immunohistochemistry Compared to Molecular Techniques for Microsatellite Instability and p53 Mutation Detection in Endometrial Cancer.

International journal of molecular sciences - 2 Mar 2023

Streel Sylvie, Salmon Alixe, Dheur Adriane, Bours Vincent, Leroi Natacha, Habran Lionel, Delbecque Katty, Goffin Frédéric, Pleyers Clémence, Kakkos Athanasios, Gonne Elodie, Seidel Laurence, Kridelka Frédéric, Gennigens Christine

Abstract excerpt

Molecular algorithms may estimate the risk of recurrence and death for patients with endometrial cancer (EC) and may impact treatment decisions. To detect microsatellite instabilities (MSI) and p53 mutations, immunohistochemistry (IHC) and molecular techniques are used. To select the most appropriate method, and to have an accurate interpretation of their results, knowledge of the performance characteristics of...

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Share to DNA Mismatch Repair
Share to Endometrial and Cervical Cancer Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genetic factors in colorectal cancer

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Identifiers

PMID: 36902292
DOI: 10.3390/ijms24054866
PMCID: PMC10002995

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