Article
Hereditary Gastric Cancer: Single-Gene or Multigene Panel Testing? A Mono-Institutional Experience.
Genes - 13 May 2023
Calvello Mariarosaria, Marabelli Monica, Gandini Sara, Marino Elena, Bernard Loris, Dal Molin Matteo, Di Cola Giulia, Zanzottera Cristina, Corso Giovanni, Fazio Nicola, Gervaso Lorenzo, Fumagalli Romario Uberto, Barberis Massimo, Guerrieri-Gonzaga Aliana, Bertario Lucio, Serrano Davide, Bonanni Bernardo
Abstract excerpt
Gastric cancer (GC) has long been a 'Cinderella' among hereditary cancers. Until recently, single-gene testing (SGT) was the only approach to identify high-risk individuals. With the spread of multigene panel testing (MGPT), a debate arose on the involvement of other genes, particularly those pertaining to homologous recombination (HR) repair. We report our mono-institutional experience in genetic counseling and...
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