Article
CDH1 on Multigene Panel Testing: Look Before You Leap.
Journal of the National Cancer Institute - 1 Apr 2020
Katona Bryson W, Clark Dana Farengo, Domchek Susan M
Abstract excerpt
Multigene panel testing (MGPT) has become a critical component of cancer risk assessment in clinical practice. As technology and access improve and costs decrease, more individuals than ever are undergoing MGPT for genetic evaluation. One gene that deserves special consideration when included on MGPT is CDH1, which codes for the cell-cell adhesion protein E-cadherin. Pathogenic and likely pathogenic germline...
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