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The roles, molecular interactions, and therapeutic value of CDK16 in human cancers

24 May 2023

Abstract excerpt

Cyclin-dependent kinase 16 (CDK16) is an orphan "cyclin-dependent kinase" (CDK) involved in the cell cycle, vesicle trafficking, spindle orientation, skeletal myogenesis, neurite outgrowth, secretory cargo transport, spermatogenesis, glucose transportation, cell apoptosis, cell growth and proliferation, metastasis, and autophagy. Human CDK16 is located on chromosome Xp11.3 and is related to X-linked congenital...

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PMID: 37236028
DOI: 10.1016/j.biopha.2023.114929

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