Article
Prevalence of SLCO1B1 single nucleotide variations and their association with hypercholesterolaemia in hypercholesterolemic patients in Gauteng, South Africa.
Xenobiotica; the fate of foreign compounds in biological systems - 1 Aug 2021
de Beer Rene, Outhoff Kim, Phulukdaree Alisa, Soma Prashilla
Abstract excerpt
Statins, the standard treatment for hypercholesterolaemia, among the most widely prescribed, have been associated with side effects, including statin intolerance. The aim of this study was to determine the background prevalence of SLCO1B1 SNVs in a randomly selected sample and to investigate if there are associations between SLCO1B1 SNVs and hypercholesterolaemia patients on statin therapy.Using Polymerase Chain...
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