The Frequency of Major ABCG2 , SLCO1B1 and CYP2C9 Variants in Asian, Native Hawaiian and Pacific Islander Women Subgroups: Implications for Personalized Statins Dosing

Abstract excerpt

Aim: The frequencies of SLCO1B1*5 and CYP2C9*2 and *3 in specific Asian, Native Hawaiian and Pacific Islander (NHPI) subgroups are unknown. Patients & methods: Repository DNA samples from 1064 women self-identifying as Filipino, Korean, Japanese, Native Hawaiian, Marshallese or Samoan and aged 18 years or older were used for targeted sequencing of three genetic variants (rs4149056, rs1799853 and rs1057910)....

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