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Article

Pathways linked to unresolved inflammation and airway remodelling characterize the transcriptome in two independent severe asthma cohorts

7 Jun 2022

Abstract excerpt

Abstract Background and objective Severe asthma (SA) is a heterogeneous disease. Transcriptomic analysis contributes to the understanding of pathogenesis necessary for developing new therapies. We sought to identify and validate mechanistic pathways of SA across two independent cohorts. Methods Transcriptomic profiles from U‐BIOPRED and Australian NOVocastrian Asthma cohorts were examined and grouped into SA,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35673765
DOI: 10.1111/resp.14302

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