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Article

The Mechanobiology of Aging

7 Dec 2015

Abstract excerpt

Aging is a complex, multifaceted process that induces a myriad of physiological changes over an extended period of time. Aging is accompanied by major biochemical and biomechanical changes at macroscopic and microscopic length scales that affect not only tissues and organs but also cells and subcellular organelles. These changes include transcriptional and epigenetic modifications; changes in energy production...

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PMID: 26643020
DOI: 10.1146/annurev-bioeng-071114-040829

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