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Human antibody libraries: A race to engineer and explore a larger diversity

1 Nov 2007

Abstract excerpt

Several recombinant antibody libraries associated with different screening technologies have been generated since the first steps of antibody engineering 15 years ago, in order to isolate human monoclonal antibodies. In this race to isolate antibody with virtually any specificity, innovative strategies have been developed to clone natural antibody repertoires or to increase library diversity beyond the scope of...

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PMID: 17981617
DOI: 10.2741/2749

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