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CLEC16A—An Emerging Master Regulator of Autoimmunity and Neurodegeneration

4 May 2023

Abstract excerpt

CLEC16A is emerging as an important genetic risk factor for several autoimmune disorders and for Parkinson disease (PD), opening new avenues for translational research and therapeutic development. While the exact role of CLEC16A in health and disease is still being elucidated, the gene plays a critical role in the regulation of autophagy, mitophagy, endocytosis, intracellular trafficking, immune function, and in...

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PMID: 37175930
DOI: 10.3390/ijms24098224

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