Article
Patho-epigenetics: histone deacetylases as targets of pathogens and therapeutics
1 Jan 2021
Abstract excerpt
In recent years, the interplay of epigenetics and infection moved into the limelight. Epigenetic regulation describes modifications in gene expression without alterations of the DNA sequence. In eukaryotes, this mechanism is central for fundamental cellular processes such as cell development and differentiation, but it is also involved in more specific tasks such as the response to infection by a pathogen. One of...
