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The role of histone deacetylases in inflammatory respiratory diseases: an update

1 Jun 2024

Abstract excerpt

INTRODUCTION: Histone deacetylases (HDACs) catalyze the removal of acetyl groups from lysine residues of histones and other proteins, generally leading to a closed chromosomal configuration and transcriptional repression. Different HDACs have distinct substrate specificities and functions in different biological processes. Accumulating evidence indicates that HDACs play a key role in the pathogenesis of multiple...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38823008
DOI: 10.1080/1744666x.2024.2363803

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