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Crystal structure of the dimerized of porcine circovirus type II replication‐related protein Rep′

12 May 2023

Abstract excerpt

Porcine circovirus type 2 (PCV2) can cause porcine circovirus-associated disease (PCVAD), which causes significant economic losses to the global pig industry annually. There are no effective antiviral drugs used to control and treat PCV2, and prevention is mainly obtained through vaccination. PCV2 genome replicates through the rolling circle replication (RCR) mechanism involving Rep and Rep', so analyzing the...

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PMID: 37171131
DOI: 10.1002/prot.26498

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