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Article

Functional analysis of cis- and trans-acting replication factors of porcine circovirus type 1.

Journal of virology - 1 Jun 2007

Steinfeldt Tobias, Finsterbusch Tim, Mankertz Annette

Abstract excerpt

The replication proteins Rep and Rep' of porcine circovirus type 1 (PCV1) are both capable of introducing and resealing strand discontinuities at the viral origin of DNA replication in vitro underlying genome amplification by rolling-circle replication. The PCV1 origin of replication encompasses the minimal binding site (MBS) of the Rep and Rep' proteins and an inverted repeat with the potential to form a...

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Identifiers

PMID: 17360750
DOI: 10.1128/JVI.02420-06
PMCID: PMC1900318

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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