Article
Mutant Rep protein of the porcine circovirus type 2 N-glycosylation:23-25aa, 256-258aa mutation reduced virus replication but 286-288aa mutation enhanced virus replication in PK-15 cells.
Veterinary microbiology - 12 Jun 2015
Shi Jianli, Peng Zhe, Fu Fang, Xu Shaojian, Xu Shengnan, Cong Xiaoyan, Yuan Xiaoyuan, Yu Jiang, Wu Jiaqiang, Sun Wenbo, Du Yijun, Li Jun, Wang Jinbao
Abstract excerpt
Porcine circovirus type 2 (PCV2) Rep protein and the splice variant Rep' protein impact genome replication. The Rep protein contains three potential N-glycosylation at positions 23-25aa (NPS), 256-258aa (NQT) and 286-288aa (NAT). Three double copy infectious clones with Rep protein N-glycosylation at positions mutations 23-25aa (DPS), 256-258aa (DQT) and 286-288aa (DAT) were constructed and their function in...
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