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Identification and Functional Analysis of the Novel ORF4 Protein Encoded by Porcine Circovirus Type 2

14 Nov 2012

Abstract excerpt

Porcine circovirus type 2 (PCV2) is the primary causative agent of porcine circovirus-associated diseases in pigs. To date, viral proteins Cap, Rep, Rep', and ORF3, encoded by the PCV2 genome, have been described. Here, transcription and translation of a novel viral gene within the PCV2 genome (designated ORF4) was determined and functionally analyzed in vitro and in vivo. Northern blot analysis indicated that...

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PMID: 23152517
DOI: 10.1128/jvi.01443-12

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