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Article

Deciphering Phenotypes from Protein Biomarkers for Translational Research with PIPER.

Journal of proteome research - 2 Jun 2023

Putty Reddy Sudhir, Alontaga Aileen Y, Welsh Eric A, Haura Eric B, Boyle Theresa A, Eschrich Steven A, Koomen John M

Abstract excerpt

Liquid chromatography-multiple reaction monitoring mass spectrometry (LC-MRM) has widespread clinical use for detection of inborn errors of metabolism, therapeutic drug monitoring, and numerous other applications. This technique detects proteolytic peptides as surrogates for protein biomarker expression, mutation, and post-translational modification in individual clinical assays and in cancer research with highly...

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Identifiers

PMID: 37171072
DOI: 10.1021/acs.jproteome.3c00137
PMCID: PMC11636645

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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