Article

The development of multiple reaction monitoring assays for liver-derived plasma.

2007-12-01

Abstract excerpt

There is wide interpatient variability in toxicity to chemotherapeutic drugs and a lack of routine clinical tests for prospectively identifying patients at risk of developing toxicity from chemotherapy. An empirically driven MS strategy has been developed to monitor liver-derived plasma proteins as potential biomarkers of early toxicity. Multiple reaction monitoring (MRM) has been used to assess 46 candidate pepti...

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Literature Corpus work: f5268b5f-a986-545c-b02a-797ed6a0076e
DOI: 10.1002/prca.200700305

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