Article

The interface between biomarker discovery and clinical validation: The tar pit of the protein biomarker pipeline.

2008-10-01

Abstract excerpt

The application of "omics" technologies to biological samples generates hundreds to thousands of biomarker candidates; however, a discouragingly small number make it through the pipeline to clinical use. This is in large part due to the incredible mismatch between the large numbers of biomarker candidates and the paucity of reliable assays and methods for validation studies. We desperately need a pipeline that rel...

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Literature Corpus work: 2e400dc2-1fe4-5985-a2ac-dff7749842aa
DOI: 10.1002/prca.200780174

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