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Article

Enzyme Inhibitors: The Best Strategy to Tackle Superbug NDM-1 and Its Variants.

International journal of molecular sciences - 24 Dec 2021

Li Xiaoting, Zhao Dongmei, Li Weina, Sun Jichao, Zhang Xiuying

Abstract excerpt

Multidrug bacterial resistance endangers clinically effective antimicrobial therapy and continues to cause major public health problems, which have been upgraded to unprecedented levels in recent years, worldwide. β-Lactam antibiotics have become an important weapon to fight against pathogen infections due to their broad spectrum. Unfortunately, the emergence of antibiotic resistance genes (ARGs) has severely...

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Identifiers

PMID: 35008622
DOI: 10.3390/ijms23010197
PMCID: PMC8745225

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