Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of L1 retrotransposons in granulocytes from patients with active systemic lupus erythematosus

10 May 2023

Abstract excerpt

BACKGROUND: Patients with systemic lupus erythematosus (SLE) have autoantibodies against the L1-encoded open-reading frame 1 protein (ORF1p). Here, we report (i) which immune cells ORF1p emanates from, (ii) which L1 loci are transcriptionally active, (iii) whether the cells express L1-dependent interferon and interferon-stimulated genes, and (iv) the effect of inhibition of L1 ORF2p by reverse transcriptase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosomal and Genetic Variations
Share to Immunodeficiency and Autoimmune Disorders
Share to Systemic Lupus Erythematosus Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37165451
DOI: 10.1186/s13100-023-00293-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of L1 retrotransposons in granulocytes from patients with active systemic lupus erythematosusPMID 37165451Read ↗

Implications of Endogenous Retroelements in the Etiopathogenesis of Systemic Lupus ErythematosusSemantic proximity Read ↗

Distinct interferon response patterns link to increased transposable element expression in leukocytes of systemic lupus erythematosus patientsSemantic proximity Read ↗

Expression of Human Endogenous Retroviruses in Systemic Lupus Erythematosus: Multiomic Integration With Gene ExpressionSemantic proximity Read ↗

Lupus Immune Complexes Drive Distinct Pro-Inflammatory Monocyte and Macrophage Populations Independent of Type I InterferonSemantic proximity Read ↗

Gene profiling of Epstein-Barr Virus and human endogenous retrovirus in peripheral blood mononuclear cells of SLE patients: immune response implicationsSemantic proximity Read ↗

The SLE Transcriptome Exhibits Evidence of Chronic Endotoxin Exposure and Has Widespread Dysregulation of Non-Coding and Coding RNAsSemantic proximity Read ↗

Neutrophil Transcriptomics in SLE: Exploring Intrinsic, Ex Vivo Adaptation, and CAR T-Cell Therapy-Induced ChangesSemantic proximity Read ↗

Sources of Pathogenic Nucleic Acids in Systemic Lupus ErythematosusSemantic proximity Read ↗

Cell-Specific Transposable Element Gene Expression Analysis Identifies Associations with Systemic Lupus Erythematosus PhenotypesSemantic proximity Read ↗

New Attempts to Define and Clarify LupusSemantic proximity Read ↗

Differential Gene Profiling of Epstein-Barr Virus and Human Endogenous Retrovirus in Peripheral Blood Mononuclear Cells of Patients with Systemic Lupus Erythematosus: Implications for Immune ResponseSemantic proximity Read ↗

Interferon and Granulopoiesis Signatures in Systemic Lupus Erythematosus BloodSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.