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Article

Implications of Endogenous Retroelements in the Etiopathogenesis of Systemic Lupus Erythematosus

2021-02-19

Abstract excerpt

Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease. While its etiology remains elusive, current understanding suggests a multifactorial process with contributions by genetic, immunologic, hormonal, and environmental factors. A hypothesis that combines several of these factors proposes that genomic elements, the L1 retrotransposons, are instrumental in SLE pathogenesis. L1 retroelements are tr...

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Literature Corpus work
49aa7097-f7d9-5e5a-bad5-69ab6dce7a8a
DOI
10.3390/jcm10040856
Open publication

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Implications of Endogenous Retroelements in the Etiopathogenesis of Systemic Lupus ErythematosusDOI 10.3390/jcm10040856
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