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Article

A joint transcriptome-wide association study across multiple tissues identifies candidate breast cancer susceptibility genes.

American journal of human genetics - 1 Jun 2023

Gao Guimin, Fiorica Peter N, McClellan Julian, Barbeira Alvaro N, Li James L, Olopade Olufunmilayo I, Im Hae Kyung, Huo Dezheng

Abstract excerpt

Genome-wide association studies (GWASs) have identified more than 200 genomic loci for breast cancer risk, but specific causal genes in most of these loci have not been identified. In fact, transcriptome-wide association studies (TWASs) of breast cancer performed using gene expression prediction models trained in breast tissue have yet to clearly identify most target genes. To identify candidate genes, we...

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Identifiers

PMID: 37164006
DOI: 10.1016/j.ajhg.2023.04.005
PMCID: PMC10257003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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