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Article

Multi-tissue transcriptome-wide association studies identified 235 genes for intrinsic subtypes of breast cancer.

Journal of the National Cancer Institute - 1 Jul 2024

Li James L, McClellan Julian C, Zhang Haoyu, Gao Guimin, Huo Dezheng

Abstract excerpt

BACKGROUND: Although genome-wide association studies (GWAS) of breast cancer (BC) identified common variants which differ between intrinsic subtypes, genes through which these variants act to impact BC risk have not been fully established. Transcriptome-wide association studies (TWAS) have identified genes associated with overall BC risk, but subtype-specific differences are largely unknown. METHODS: We performed...

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Source

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Identifiers

PMID: 38400758
DOI: 10.1093/jnci/djae041
PMCID: PMC11223833

Genes

CHEK2
MDM4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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