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Ability of the MeltPro MTB/PZA Assay to Detect Susceptibility to Pyrazinamide in Rifampin-Resistant Tuberculosis Patients.

Microbiology spectrum - 15 Jun 2023

Li Rong, Li Yang, Chen Xinchang, Jia Lina, Yu Hongying, Huang Ya, Wu Qianhong, Xiao Mingying, Ge Shijia, Zhang Yilin, Feng Zhen, Li Qingge, Xu Ye, Shi Wenzhi, Sun Feng, Zhang Wenhong

Abstract excerpt

Prediction of susceptibility to pyrazinamide (PZA) directly from sputum has been challenging. The MeltPro MTB/PZA assay, based on melting curve analysis, can simultaneously detect Mycobacterium tuberculosis and the resistance to PZA from sputum. We aimed to evaluate the MeltPro MTB/PZA assay to predict PZA resistance among rifampin-resistant tuberculosis (RR-TB) patients. We prospectively enrolled RR-TB patients...

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Identifiers

PMID: 37162355
DOI: 10.1128/spectrum.04836-22
PMCID: PMC10269598

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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