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Article

In vivo characterization of sAC null sperm

21 Apr 2023

Abstract excerpt

Targeted disruption of the soluble adenylyl cyclase (ADCY10; sAC) gene results in male-specific sterility without affecting spermatogenesis, mating behavior, or spermatozoa morphology and count; however, it dramatically impairs sperm motility and prevents capacitation. These phenotypes were identified in sperm from sAC null mice surgically extracted from the epididymis and studied in vitro. Epididymal sperm are...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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PMID: 37152282
DOI: 10.3389/fcell.2023.1134051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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