Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Epididymal protein Rnase10 is required for post‐testicular sperm maturation and male fertility

29 Jun 2012

Abstract excerpt

Eutherian spermatozoa are dependent on the environment of the proximal epididymis to complete their maturation; however, no specific epididymal factors that mediate this process have so far been identified. Here, we show that targeted disruption of the novel gene Rnase10 encoding a secreted proximal epididymal protein in the mouse results in a binding defect in spermatozoa and their inability to pass through the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Reproductive Biology and Fertility
Share to Sperm and Testicular Function

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 22750516
DOI: 10.1096/fj.12-205211

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Epididymal protein Rnase10 is required for post‐testicular sperm maturation and male fertilityPMID 22750516Read ↗

Tmprss12 is required for sperm motility and uterotubal junction migration in mice†Semantic proximity Read ↗

Deletion ofAdam6inMus musculusleads to male subfertility and deficits in sperm ascent into the oviductSemantic proximity Read ↗

Reduced Fertility and Altered Epididymal and Sperm Integrity in Mice Lacking ADAM71Semantic proximity Read ↗

Mice expressing aberrant sperm-specific protein PMIS2 produce normal-looking but fertilization-incompetent spermatozoaSemantic proximity Read ↗

Disruption of ADAM3 Impairs the Migration of Sperm into Oviduct in Mouse1Semantic proximity Read ↗

Testicular and epididymal ADAMs: expression and function during fertilizationSemantic proximity Read ↗

Serine protease PRSS55 is crucial for male mouse fertility via affecting sperm migration and sperm–egg bindingSemantic proximity Read ↗

Mice deficient for soluble adenylyl cyclase are infertile because of a severe sperm-motility defectSemantic proximity Read ↗

New insights into epididymal biology and functionSemantic proximity Read ↗

Epididymal epithelium: Its contribution to the formation of a luminal fluid microenvironmentSemantic proximity Read ↗

Epididymal SPAM1 Is a Marker for Sperm Maturation in the Mouse1Semantic proximity Read ↗

Protein disulfide isomerase homolog PDILT is required for quality control of sperm membrane protein ADAM3 and male fertilitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.