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Article

Evidence for multiple distinctly localized adenylyl cyclase isoforms in mammalian spermatozoa

25 Aug 2003

Abstract excerpt

In addition to a bicarbonate-regulated soluble adenylyl cyclase (sAC), mammalian spermatozoa, like somatic cells, appear to contain receptor/G protein-regulated AC activity that contributes to the modulation of specialized cell processes. This study provides evidence that agents, known to influence somatic membrane-associated AC (mAC) but apparently not germ cell sAC, can modulate cAMP production and functional...

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Identifiers

PMID: 12950106
DOI: 10.1002/mrd.10344

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