Article
Adolescent anxiety and pain problems: A joint, genome-wide investigation and pathway-based analysis.
PloS one - 1 Jan 2023
Mascheretti Sara, Forni Diego, Lampis Valentina, Fumagalli Luca, Paquin Stéphane, Andlauer Till F M, Wang Wei, Dionne Ginette, Brendgen Mara R, Vitaro Frank, Ouellet-Morin Isabelle, Rouleau Guy, Gouin Jean-Philippe, Côté Sylvana, Tremblay Richard E, Turecki Gustavo, Garon-Carrier Gabrielle, Boivin Michel, Battaglia Marco
Abstract excerpt
Both common pain and anxiety problems are widespread, debilitating and often begin in childhood-adolescence. Twin studies indicate that this co-occurrence is likely due to shared elements of risk, rather than reciprocal causation. A joint genome-wide investigation and pathway/network-based analysis of adolescent anxiety and pain problems can identify genetic pathways that subserve shared etiopathogenetic...
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