Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Adolescent pain reports share genetic overlap with adult chronic pain conditions: A polygenic score analysis using the ABCD study.

The journal of pain - 1 Jun 2026

Rader Lydia, Zorina-Lichtenwalter Katerina, Gustavson Daniel E, Wager Tor D, Friedman Naomi P

Abstract excerpt

Adolescent pain complaints may be related to genetic risk for chronic pain across the life course. Identifying whether adolescent pain is genetically linked to chronic pain in adulthood can advance understanding of pain etiology and inform early intervention. Two waves of pain assessments were used from the Adolescent Brain Cognitive Development (ABCD) study, a population-based sample of 11,876 adolescents. The...

Topics

Humans
Chronic Pain
Genetic Risk Score
Adolescent
Female
Genome-Wide Association Study
Male
Child
Adult
Multifactorial Inheritance
Musculoskeletal Pain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Young Adult

Genetic Predisposition to Disease

Source

Identifiers

PMID: 41831663
DOI: 10.1016/j.jpain.2026.106260

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Adolescent pain reports share genetic overlap with adult chronic pain conditions: A polygenic score analysis using the ABCD study.PMID 41831663Read ↗

Genetic and epigenetic epidemiology of chronic widespread painSemantic proximity Read ↗

Genetic risk shared across 24 chronic pain conditions: identification and characterization with genomic structural equation modelingSemantic proximity Read ↗

A Shared Genetic Signature for Common Chronic Pain Conditions and its Impact on Biopsychosocial Traits.Semantic proximity Read ↗

A shared genetic signature for common chronic pain conditions and its impact on biopsychosocial traitsSemantic proximity Read ↗

Adolescent anxiety and pain problems: A joint, genome-wide investigation and pathway-based analysis.Semantic proximity Read ↗

Causal evidence linking chronic pain genetics to late-onset asthma via the nervous system.Semantic proximity Read ↗

Genome-wide association study of multisite chronic pain in UK BiobankSemantic proximity Read ↗

Genetic and Environmental Risk for Chronic Pain and the Contribution of Risk Variants for Major Depressive Disorder: A Family-Based Mixed-Model AnalysisSemantic proximity Read ↗

Development and Replication of a Genome-Wide Polygenic Risk Score for Chronic Back PainSemantic proximity Read ↗

Heritability of chronic pain in 2195 extended families.Semantic proximity Read ↗

Heritability of musculoskeletal pain and pain sensitivity phenotypes: 2 generations of the Raine Study.Semantic proximity Read ↗

Characterizing phenotypes and clinical and health utilization associations of young people with chronic pain: latent class analysis using the electronic Persistent Pain Outcomes Collaboration database.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.