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Article

Depression and 24 gastrointestinal diseases: a Mendelian randomization study.

Translational psychiatry - 4 May 2023

Ruan Xixian, Chen Jie, Sun Yuhao, Zhang Yao, Zhao Jianhui, Wang Xiaoyan, Li Xue, Yuan Shuai, Larsson Susanna C

Abstract excerpt

The causality of the association between depression and gastrointestinal diseases is undetermined. We conducted Mendelian randomization (MR) analyses to systematically explore the associations of depression with 24 gastrointestinal diseases. Independent genetic variants associated with depression at the genome-wide significance level were selected as instrumental variables. Genetic associations with 24...

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Identifiers

PMID: 37142593
DOI: 10.1038/s41398-023-02459-6
PMCID: PMC10160129

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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