Article
Depression and risk of gastrointestinal disorders: a comprehensive two-sample Mendelian randomization study of European ancestry.
Psychological medicine - 1 Nov 2023
Chen Dongze, Zhang Yali, Huang Tao, Jia Jinzhu
Abstract excerpt
BACKGROUND: Major depressive disorder (MDD) is clinically documented to co-occur with multiple gastrointestinal disorders (GID), but the potential causal relationship between them remains unclear. We aimed to evaluate the potential causal relationship of MDD with 4 GID [gastroesophageal reflux disease (GERD), irritable bowel syndrome (IBS), peptic ulcer disease (PUD), and non-alcoholic fatty liver disease...
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