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Article

Mendelian randomization study of gastroesophageal reflux disease and major depression.

PloS one - 1 Jan 2023

Zheng Xiaofei, Zhou Xin, Tong Li, Gu Wang, Wang Siyu, Yuang Wenkang, Zhang Chong, Zhang Chaoyang, Zhang Chao, Wan Bangbei

Abstract excerpt

This study systematically investigated the causal relationship between gastroesophageal reflux disease (GERD) and major depression (MD). Single-nucleotide polymorphisms (SNPs) associated with disorders of interest were screened via the genome-wide association study (GWAS) enrolling individuals of European descent. Summary-level data for GERD and MD were extracted from the UK Biobank. The inverse-variance-weighted...

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Identifiers

PMID: 37768900
DOI: 10.1371/journal.pone.0291086
PMCID: PMC10538746

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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