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Article

ERCC1 and ERCC2 polymorphisms predict clinical outcomes of oxaliplatin-based chemotherapies in gastric and colorectal cancer: a systemic review and meta-analysis.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Mar 2011

Yin Ming, Yan Jingrong, Martinez-Balibrea Eva, Graziano Francesco, Lenz Heinz-Josef, Kim Hyo-Jin, Robert Jacques, Im Seock-Ah, Wang Wei-Shu, Etienne-Grimaldi Marie-Christine, Wei Qingyi

Abstract excerpt

PURPOSE: Nucleotide excision repair (NER) modulates platinum-based chemotherapeutic efficacy by removing drug-produced DNA damage. To summarize published data on the association between polymorphisms of NER genes (ERCC1 and ERCC2) and responses to oxaliplatin-based chemotherapies, we carried out...

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Identifiers

PMID: 21278243
DOI: 10.1158/1078-0432.CCR-10-2169
PMCID: PMC3060288

Genes

ERCC1
ERCC2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21278243-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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