Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hyperglycemia-induced oxidative stress and epigenetic regulation of ET-1 gene in endothelial cells

17 Apr 2023

Abstract excerpt

Introduction: Hyperglycemia-induced endothelial dysfunction and the subsequent increase of oxidative stress could lead to aberrant regulation of various genes which are responsible for a range of functions. This study aims to find out how hyperglycemia affect oxidative stress and then the expression and methylation of endothelin 1 (ET-1) gene in in human umbilical vein endothelial cells (HUVEC). Methods: Cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced Glycation End Products research
Share to Diabetes, Cardiovascular Risks, and Lipoproteins
Share to Renin-Angiotensin System Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37139232
DOI: 10.3389/fgene.2023.1167773

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hyperglycemia-induced oxidative stress and epigenetic regulation of ET-1 gene in endothelial cellsPMID 37139232Read ↗

Identification and Verification of Candidate Genes Regulating Human Umbilical Vein Endothelial Cells Behavior Under HyperglycemiaSemantic proximity Read ↗

Analysis of long non-coding RNA expression profiles in high-glucose treated vascular endothelial cellsSemantic proximity Read ↗

Palmitate-Associated ET-1 and PAI-1 Transcriptional Responses Under High-Glucose Conditions in HUVECs: An Exploratory Glucolipotoxic Stress ModelSemantic proximity Read ↗

Role of epigenetic mechanisms in the vascular complications of diabetes.Semantic proximity Read ↗

Role of DNA Methylation in Ischemic-Hypoxic Endothelial Cells and its Clinical Implications in AMI PatientsSemantic proximity Read ↗

Hyperglycemic conditions induce rapid cell dysfunction-promoting transcriptional alterations in human aortic endothelial cellsSemantic proximity Read ↗

Hyperglycemia and redox status regulate RUNX2 DNA-binding and an angiogenic phenotype in endothelial cells.Semantic proximity Read ↗

Targeting High Glucose-Induced Epigenetic Modifications at Cardiac Levels: The Role of SGLT2 and SGLT2 InhibitorsSemantic proximity Read ↗

Metformin prevented high glucose-induced endothelial reactive oxygen species via OGG1 in an AMPKα-Lin-28 dependent pathwaySemantic proximity Read ↗

Targeting high glucose-induced epigenetic modifications at cardiac level: the role of SGLT2 and SGLT2 inhibitorsSemantic proximity Read ↗

Regulation of SIRT1 by Oxidative Stress-Responsive miRNAs and a Systematic Approach to Identify Its Role in the EndotheliumSemantic proximity Read ↗

Atheroprone flow enhances the endothelial-to-mesenchymal transitionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.