Article

Targeting High Glucose-Induced Epigenetic Modifications at Cardiac Levels: The Role of SGLT2 and SGLT2 Inhibitors

2022-11-29

Abstract excerpt

<h4>Background: </h4> Sodium-glucose co-transporters inhibitors showed many beneficial effects at the cardiovascular level. Several mechanisms of action have been identified. However, no data are reported on their capability to act via epigenetic mechanisms. Therefore, this study aimed to investigate the ability of SGLT2 inhibitors to induce protective effects at the cardiovascular level by acting on DNA methylati...

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Literature Corpus work: c1d67c74-3d6b-547c-bf4e-300799cc1057
DOI: 10.21203/rs.3.rs-2300456/v1

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