Article
Role of epigenetic mechanisms in the vascular complications of diabetes.
Sub-cellular biochemistry - 1 Jan 2013
Reddy Marpadga A, Natarajan Rama
Abstract excerpt
Diabetes and metabolic disorders are leading causes of micro- and macrovascular complications. Furthermore, efforts to treat these complications are hampered by metabolic memory, a phenomenon in which prior exposure to hyperglycemia predisposes diabetic patients to the continued development of vascular diseases despite subsequent glycemic control. Persistently increased levels of oxidant stress and inflammatory...
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