Article
Clinical characteristics and prognosis analysis of patients with de novo ASXL1-mutated AML treated with the C-HUNAN-AML-15 protocol: A multicenter study by the South China Pediatric AML Collaborative Group.
Cancer medicine - 1 Jun 2023
Zeng Minhui, Chen Keke, Tian Xin, Zou Runying, Feng Xiaoqin, Li Chunfu, Li Jian, Zheng Mincui, Mai Huirong, Yang Lihua, He Yingyi, Xu Honggui, Wen Hong, He Xiangling
Abstract excerpt
BACKGROUND: ASXL1 mutation is an independent prognostic factor in adult acute myeloid leukemia (AML), but its effect on the prognosis of pediatric AML is poorly understood. AIMS: This study aimed to investigate the clinical characteristics and prognostic factors of ASXL1-mutant pediatric AML from a large Chinese multicenter cohort. METHODS: A total of 584 pediatric patients with newly diagnosed AML from 10...
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