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Clinical characteristics and prognostic study of adult acute myeloid leukemia patients with ASXL1 mutations.

Hematology (Amsterdam, Netherlands) - 1 Dec 2020

Lin Yun, Wang Yaping, Zheng Yi, Wang Zechuan, Wang Yanni, Wang Shaoyuan

Abstract excerpt

Objectives: A total of 156 adult acute myeloid leukemia (AML) patients were enrolled in this study to explore the clinical characteristics and prognostic impact of ASXL1 mutations. Methods: Clinical characteristics, prognostic impact and the association between ASXL1 mutations and some other mutations were analyzed. Results: We found ASXL1 mutations were most frequently found in M5 subtype and intermediate risk...

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PMID: 33250015
DOI: 10.1080/16078454.2020.1847801

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