Article
Allogeneic hematopoietic stem cell transplantation could improve the survival of acute myeloid leukemia patients with ASXL1 mutations.
Hematology (Amsterdam, Netherlands) - 1 Dec 2021
Zhou Lili, An Jingnan, Hou Chang, Ding Zixuan, Qiu Huiying, Tang Xiaowen, Sun Aining, Chen Suning, Xu Yang, Liu Tianhui, Wu Depei
Abstract excerpt
Objective: To discover the function of allogeneic hematopoietic stem cell transplantation (allo-HSCT) in ASXL1-mutated acute myeloid leukemia (AML) patients.Methods: We analyzed the prognostic value of ASXL1 mutations and explored the role of allo-HSCT in 581 AML patients.Results: According to the definition of intermediate- and adverse-risk AML groups in the European Leukemia Net (ELN), ASXL1-mutated patients...
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